FIMA Data Integration Module

FIMA
Data Integration Module

In PubMed: " Euphorbia gnyoniana "

Results:

01 - 02 - 03 - 04 - 05 - 06 - 07 - 08 - 09 - 10 - 11 - 12 - 13 - 14 - 15 - 16

Title:
Purification and partial characterization of a mitogenic lectin from the latex of Euphorbia marginata.

Journal:
Biochimica et biophysica acta. 1993 Aug;1158(1):33-9

Authors:
Stirpe F, Licastro F, Morini MC, Parente A, Savino G, Abbondanza A, Bolognesi A, Falasca AI, Rossi CA.

Abstract:
A lectin was purified from the latex of Euphorbia marginata by affinity chromatography on acid-treated Sepharose 6B and elution with lactose. The lectin is a glycoprotein composed of two identical subunits with M(r) 30,000, approx. The haemagglutinating activity of the lectin is not specific for any human blood group, and is inhibited by galactose and galactose-containing sugars and by gentiobiose. The lectin is strongly mitogenic for human T-lymphocytes and induces the release of interleukin-1 beta and tumor necrosis factor-alpha from cultured mononuclear cells.

See full PubMed entry: http://www.ncbi.nlm.nih.gov/pubmed/8353129

FIMA Data Integration Module is based on an expanded and improved version of the algorithm reported in the following reference. Primary citation: Abdelkrim Rachedi et al., GABAagent: a system for integrating data on GABA receptors. Bioinformatics. 2000 Apr;16(4):301-12.