3D-structure - 3QX3:
| Entry Summary |
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Entry | 3qx3 | |
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Header | ISOMERASE/DNA/ISOMERASE INHIBITOR
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Title | HUMAN TOPOISOMERASE IIBETA IN COMPLEX WITH DNA AND ETOPOSIDE |
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Authors | C. C. WU, T. K. LI, L. FARH, L. Y. LIN, T. S. LIN, Y. J. YU, T. J. YENC. W. CHIANG, N. L. CHAN |
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Primary Title | STRUCTURAL BASIS OF TYPE II TOPOISOMERASE INHIBITIO
ANTICANCER DRUG ETOPOSIDE |
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Reference | SCIENCE, , , Vol.333459, 2011 |
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Experiment | Method: X-RAY DIFFRACTION
Parameters: Resolution: 2.16 Angs, Ref-Value: 17, Space Group: P 1 21 1
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Chains | A, B, C, E, D, F |
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Biological Unit | Biological Unit as provided by the RCSB PDB |
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Hexamer 1: | A B C D E F | |
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Enzyme | 5.99.1.3 (Name(s) and Reaction(s) catalysed) |
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Source | Homo sapiens |
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Taxonomy | 9606 |
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UniProt | Chain A: Q02880,Chain B: Q02880,Chain C: 1 8,Chain E: 1 8,Chain D: 9 20,Chain F: 9 20, |
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| Geometry: [Spots in Red indicate possible wrong φ & ψ values]
| | 3D-View - PDBe Mol*
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