3D-structure - 4P5E:
| Entry Summary |
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Entry | 4p5e | |
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Header | HYDROLASE
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Title | CRYSTAL STRUCTURE OF HUMAN DNPH1 (RCL) WITH 6-NAPHTHYL-PURIN RIBOSIDE-MONOPHOSPHATE |
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Authors | C. AMIABLE, J. PAOLETTI, A. HAOUZ, A. PADILLA, G. LABESSE, P. A. KAMINSKI, S. POCHET |
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Primary Title | 6-(HETERO)ARYLPURINE NUCLEOTIDES AS INHIBITORS OF T
ONCOGENIC TARGET DNPH1: SYNTHESIS, STRUCTURAL STUDI
CYTOTOXIC ACTIVITIES. |
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Reference | EUR.J.MED.CHEM., Vol.85C418, 2014 |
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Experiment | Method: X-RAY DIFFRACTION
Parameters: Resolution: 1.35 Angs, Ref-Value: 15.6, Space Group: P 1 21 1
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Chains | A, B |
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Biological Unit | Biological Unit as provided by the RCSB PDB |
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Dimer 1: | B A | |
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Dimer 2: | A B | |
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Enzyme | 3.2.2.- (Name(s) and Reaction(s) catalysed) |
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Source | Homo sapiens |
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Taxonomy | 9606 |
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UniProt | Chain A: O43598,Chain B: O43598, |
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| Geometry: [Spots in Red indicate possible wrong φ & ψ values]
| | 3D-View - PDBe Mol*
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