Title: LRP16 is fused to RUNX1 in monocytic leukemia cell line with t(11;21)(q13;q22). | Journal: European journal of haematology. 2007 Jul;79(1):25-31 | Authors: Imagama S, Abe A, Suzuki M, Hayakawa F, Katsumi A, Emi N, Kiyoi H, Naoe T. | Abstract: The RUNX1 (also known as AML1) gene is observed frequently as the target of chromosomal rearrangements in human acute leukemia. We describe here a previously unreported rearrangement, t(11;21)(q13;q22), that disrupts the RUNX1 gene in a patient with acute leukemia and the molecular analysis of the fusion gene. | See full PubMed entry: http://www.ncbi.nlm.nih.gov/pubmed/17532767 |
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