Title: The stationary-phase sigma factor sigma(S) is responsible for the resistance of Escherichia coli stationary-phase cells to mazEF-mediated cell death. |
Journal: Journal of bacteriology. 2009 May;191(9):3177-82 |
Authors: Kolodkin-Gal I, Engelberg-Kulka H. |
Abstract: Escherichia coli mazEF is a toxin-antitoxin gene module that mediates cell death during exponential-phase cellular growth through either reactive oxygen species (ROS)-dependent or ROS-independent pathways. Here, we found that the stationary-phase sigma factor sigma(S) was responsible for the resistance to mazEF-mediated cell death during stationary growth phase. Deletion of rpoS, the gene encoding sigma(S) from the bacterial chromosome, permitted mazEF-mediated cell death during stationary growth phase. |
See full PubMed entry: http://www.ncbi.nlm.nih.gov/pubmed/19251848 |