Title: The dinB operon and spontaneous mutation in Escherichia coli. | Journal: Journal of bacteriology. 2003 Jul;185(13):3972-7 | Authors: McKenzie GJ, Magner DB, Lee PL, Rosenberg SM. | Abstract: Apparently conflicting data regarding the role of SOS-inducible, error-prone DNA polymerase IV (DinB) in spontaneous mutation are resolved by the finding that mutation is reduced by a polar allele with which dinB and neighboring yafN are deleted but not by two nonpolar dinB alleles. We demonstrate the existence of a dinB operon that contains four genes, dinB-yafN-yafO-yafP. The results imply a role for yafN, yafO, and/or yafP in spontaneous mutation. | See full PubMed entry: http://www.ncbi.nlm.nih.gov/pubmed/12813093 |
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