Title: Effects of streptomycin resistance mutations on posttranslational modification of ribosomal protein S12. |
Journal: Journal of bacteriology. 2006 Mar;188(5):2020-3 |
Authors: Carr JF, Hamburg DM, Gregory ST, Limbach PA, Dahlberg AE. |
Abstract: Ribosomal protein S12 contains a highly conserved aspartic acid residue that is posttranslationally beta-methylthiolated. Using mass spectrometry, we have determined the modification states of several S12 mutants of Thermus thermophilus and conclude that beta-methylthiolation is not a determinant of the streptomycin phenotype. |
See full PubMed entry: http://www.ncbi.nlm.nih.gov/pubmed/16484214 |