Title: Partial amino acid sequence of penicillinase coded by Escherichia coli plasmid R6K. |
Journal: Proceedings of the National Academy of Sciences of the United States of America. 1978 Aug;75(8):3732-6 |
Authors: Ambler RP, Scott GK. |
Abstract: Direct studies of the amino acid sequence of an Escherichia coli plasmid-coded penicillinase (penicillin amido-beta-lactamhydrolase, EC 3.5.2.6) are in complete agreement with results derived from the translation of the DNA sequence of a related plasmid, apart from a single amino acid substitution. This penicillinase from a Gram-negative bacterium shows 30-35% identity with functionally similar enzymes from Gram-positive bacteria. This paper should be read in conjunction with the report of the DNA sequence of the gene. |
See full PubMed entry: http://www.ncbi.nlm.nih.gov/pubmed/358199 |