BRAID Data Integration Module

BRAID
Data Integration Module

In PubMed: " Linezolid "

Results:

1 - 2 - 3 - 4 - 5 - 6 - 7 - 8

Title:
First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States.

Journal:
Antimicrobial agents and chemotherapy. 2008 Jun;52(6):2244-6

Authors:
Mendes RE, Deshpande LM, Castanheira M, DiPersio J, Saubolle MA, Jones RN.

Abstract:
Linezolid resistance has dominantly been mediated by mutations in 23S rRNA or ribosomal protein L4 genes. Recently, cfr has demonstrated the ability to produce a phenotype of resistance to not only oxazolidinones, but also other antimicrobial classes (phenicols, lincosamides, pleuromutilins, and streptogramin A). We describe the first detection of cfr-mediated linezolid resistance in Staphylococcus aureus and Staphylococcus epidermidis recovered from human infection cases monitored during the 2007 LEADER Program.

See full PubMed entry: http://www.ncbi.nlm.nih.gov/pubmed/18391032

BRAID Data Integration Module is based on an improved version of the algorithm reported in the following reference. Primary citation: Abdelkrim Rachedi et al., GABAagent: a system for integrating data on GABA receptors. Bioinformatics. 2000 Apr;16(4):301-12.